Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Mercaptoethanesulfonic acid → Mafosfamide Sodium Salt
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Mercaptoethanesulfonic acid | HCID 598 | — |
| 반응물 | 4-Hydroxycyclophosphamide | HCID 99735 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | Mafosfamide Sodium Salt | HCID 104746 | — |
반응 단계
0.8 g (3.0 mmol) of 4-hydroxycyclophosphamide in 3 ml of water were mixed with 420 mg (3.0 mmol) of 2-mercaptoethanesulphonic acid, with ice water cooling. After 1 hour, the mixture was concentrated under high vacuum and was crystallised.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04623742 |
| 출처 데이터셋 | uspto-grants-1986_11 |
| ORD ID | ord-619ed1eb67204fd4b7bf039408ffcadd |
| 출처 메모 | uspto-grants-1986_11 |