Ethanol → Ethyl [2,3-dichloro-4-(6-ethyl-3-oxo-1-cyclohexen-1-yl)-phenoxy]acetate

HRID 1732178노트

반응식

HRID 1732178 반응식
[Cl:1][C:2]1[C:12]([Cl:13])=[C:11]([C:14]2[CH:19]([CH2:20][CH3:21])[CH2:18][CH2:17][C:16](=[O:22])[CH:15]=2)[CH:10]=[CH:9][C:3]=1[O:4][CH2:5][C:6]([OH:8])=[O:7].[CH2:23](O)[CH3:24]>S(=O)(=O)(O)O>[Cl:1][C:2]1[C:12]([Cl:13])=[C:11]([C:14]2[CH:19]([CH2:20][CH3:21])[CH2:18][CH2:17][C:16](=[O:22])[CH:15]=2)[CH:10]=[CH:9][C:3]=1[O:4][CH2:5][C:6]([O:8][CH2:23][CH3:24])=[O:7]

참가 물질

4

반응물 2

HCID 702EthanolHCID 10759778[2,3-Dichloro-4-(6-ethyl-3-oxo-1-cyclohexen-1-yl)phenoxy]acetic acid

생성물 1

HCID 13749111Ethyl [2,3-dichloro-4-(6-ethyl-3-oxo-1-cyclohexen-1-yl)-phenoxy]acetate

시약·촉매·용매 1

HCID 1118Sulfuric Acid촉매

실험 절차

A stirred solution of [2,3-dichloro-4-(6-ethyl-3-oxo-1-cyclohexen-1-yl)phenoxy]acetic acid (3.43 g, 0.01 mole) in ethanol (50 ml) containing sulfuric acid (4 drops) was heated at reflux for 4 hours. The ethanol was evaporated at reduced pressure, the residue dissolved in ether, washed with dilute sodium hydroxide, water, dried over magnesium sulfate and evaporated in vacuo to give 3.31 g of ethyl [2,3-dichloro-4-(6-ethyl-3-oxo-1-cyclohexen-1-yl)-phenoxy]acetate which melted at 110°-112° C.

후처리

  1. temperaturewas heated
  2. temperatureat reflux for 4 hours
  3. customThe ethanol was evaporated at reduced pressure
  4. dissolutionthe residue dissolved in ether
  5. washwashed with dilute sodium hydroxide, water
  6. dry with materialdried over magnesium sulfate
  7. customevaporated in vacuo

출처 및 근거

ORD 기록
ord-27a63db16c5442c7a29ebdb35af297ee
출처 데이터셋
uspto-grants-1986_11
특허 번호
US04625047

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