Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl Bromide → N-Ethyl-N-methyl-2-thiophene methanamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl Bromide | HCID 6332 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | N-Methyl-1-(thiophen-2-yl)methanamine | HCID 436153 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Toluene | HCID 1140 | — |
| 용매 | Sodium Bicarbonate | HCID 516892 | — |
| 생성물 | N-Ethyl-N-methyl-2-thiophene methanamine | HCID 12788071 | — |
반응 단계
Bromoethane (150 ml), triethylamine (7.3 ml) and N-methyl-2-thiophenemethanamine (21.2 g) were stirred at room temperature in toluene (212 ml) for 4 days. The solution was diluted with water, saturated with sodium bicarbonate and extracted with ethyl acetate. The organic extracts were distilled to give the title compound as an oil (13.6 g) b.p. 46° (16 mm).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04239769 |
| 출처 데이터셋 | uspto-grants-1980_12 |
| ORD ID | ord-2cc545f257c747f1846a3e4260f3340f |
| 출처 메모 | uspto-grants-1980_12 |