Ammonia → HCID 12788083, 화합물
반응식
C([O:3][C:4](=O)[CH2:5][O:6][CH2:7][C:8]1[S:9][C:10]([CH2:13][N:14]([CH3:16])[CH3:15])=[CH:11][CH:12]=1)C.[NH3:18]>C(O)C>[CH3:15][N:14]([CH2:13][C:10]1[S:9][C:8]([CH2:7][O:6][CH2:5][C:4]([NH2:18])=[O:3])=[CH:12][CH:11]=1)[CH3:16]참가 물질
4
실험 절차
A solution of [[5-(N,N-dimethylaminomethyl)2-thienyl]methoxy] acetic acid ethyl ester (4.0 g) in a mixture of 0.88 ammonia solution (75 ml) and ethanol (75 ml) was stirred for 1 hr at room temperature. The solvent was removed and the residue recrystallised from a 1:1 mixture of benzene and petroleum spirit (b.p. 60°-80°) to afford a white crystalline solid (3.2 g) m.p. 86.5°-95°. NMR (CDCl3) 7.71, s, (6H); 6.38, s, (2H); 6.00, s, (2H); 5.30, s, (2H); 3.5, br, (2H); 3.12, q, (2H).
후처리
- customThe solvent was removed
- customthe residue recrystallised from a 1:1 mixture of benzene and petroleum spirit (b.p. 60°-80°)
출처 및 근거
- ORD 기록
- ord-55d91735dca14a72904f46d886d10b16
- 출처 데이터셋
- uspto-grants-1980_12
- 특허 번호
- US04239769
반응 노트
불러오는 중…