Sulfuryl chloride → (3-Hydroxy-thiophen-2-yl)-phenyl-methanone

반응식

[OH:1][CH:2]1[CH:6]=[CH:5][S:4][CH:3]1[C:7](=[O:14])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.S(Cl)(Cl)(=O)=O>>[OH:1][C:2]1[CH:6]=[CH:5][S:4][C:3]=1[C:7](=[O:14])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

참가 물질

반응물 2

HCID 24648Sulfuryl chloride

HCID 20300160HCID 20300160, 화합물

생성물 1

HCID 135542479(3-Hydroxy-thiophen-2-yl)-phenyl-methanone수율 82%

실험 절차

The compound is prepared by the method described in Example 14c) from 20.6 parts of 3-hydroxy-2-benzoyldihydrothiophene and 6.75 parts of sulfuryl chloride. 16.7 parts (82% of theory) of 3-hydroxy-2-benzoylthiophene of boiling point 127°-132° C./0.5 mbar and melting point 53°-57° C. are obtained.

후처리

customThe compound is prepared by the method

출처 및 근거

ORD 기록: ord-fbca0a4e2e2c4395af434a24992cfcb3
출처 데이터셋: uspto-grants-1980_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04239897

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