Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 2-Chloro-N-(3-cyano-4,5-dimethyl-2-furanyl)acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Chloroacetyl chloride | HCID 6577 | — |
| 반응물 | 2-Amino-4,5-dimethyl-3-furancarbonitrile | HCID 290220 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 2-Chloro-N-(3-cyano-4,5-dimethyl-2-furanyl)acetamide | HCID 16227354 | 122.3% |
반응 단계
20.4 g (0.1 mole) of 2-amino-3-cyano-4,5-dimethylfurane and 17.5 g (0.155 mole) of chloroacetyl chloride were boiled in 200 ml of toluene until the evolution of hydrogen chloride had subsided. Thereafter, the solvent was evaporated off under reduced pressure and the residue was recrystallized from ethyl acetate. 26 g of 2-chloroacetylamino-3-cyano-4,5-dimethylfurane of melting point 114° C. were obtained in this manner.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04240820 |
| 출처 데이터셋 | uspto-grants-1980_12 |
| ORD ID | ord-732f528106744e908873ac48e9d38c0e |
| 출처 메모 | uspto-grants-1980_12 |