HCID 54200145, 화합물 → HCID 54282494, 화합물
반응식
C([S:4][CH:5]([C:16]([F:19])([F:18])[F:17])[C:6]([N:8]1[CH2:15][CH2:14][CH2:13][C@H:9]1[C:10]([OH:12])=[O:11])=[O:7])(=O)C>O.N>[SH:4][CH:5]([C:16]([F:19])([F:17])[F:18])[C:6]([N:8]1[CH2:15][CH2:14][CH2:13][C@H:9]1[C:10]([OH:12])=[O:11])=[O:7]참가 물질
4
실험 절차
1-(2-Acetylthio-3,3,3-trifluoropropanoyl)-L-proline (4 g.) is dissolved in a mixture of water (8 ml.) and concentrated ammonia (8 ml.) under a blanket of nitrogen. After thirty minutes at room temperature, the reaction mixture is acidified and extracted with ethyl acetate. The organic phase is dried over magnesium sulfate and concentrated to dryness in vacuo to yield 1-(2-mercapto-3,3,3-trifluoropropanoyl)-L-proline.
후처리
- waitAfter thirty minutes at room temperature
- extractionextracted with ethyl acetate
- dry with materialThe organic phase is dried over magnesium sulfate
- concentrationconcentrated to dryness in vacuo
출처 및 근거
- ORD 기록
- ord-3bd01a04bc974cb69a4f6b647aa0c1c6
- 출처 데이터셋
- uspto-grants-1980_12
- 특허 번호
- US04241076
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