Hydrazine → 5-(4-Chlorophenyl)-2-hydrazinopyridine

HRID 1733574

반응식

HRID 1733574 반응식
Cl[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([Cl:14])=[CH:10][CH:9]=2)=[CH:4][N:3]=1.[NH2:15][NH2:16]>N1C=CC=CC=1>[Cl:14][C:11]1[CH:12]=[CH:13][C:8]([C:5]2[CH:6]=[CH:7][C:2]([NH:15][NH2:16])=[N:3][CH:4]=2)=[CH:9][CH:10]=1

참가 물질

4

반응물 2

HCID 9321HydrazineHCID 100365542-Chloro-5-(4-chlorophenyl)pyridine

생성물 1

HCID 203000925-(4-Chlorophenyl)-2-hydrazinopyridine

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

A mixture of 21.1 g. of 2-chloro-5-(4-chlorophenyl)pyridine and 19.5 g. of 95% hydrazine in 200 ml. of pyridine is heated at reflux temperature for 48 hours. The reaction mixture is cooled, poured into an ice-water mixture and filtered. The solid is collected, washed with water and air dried to yield 17.0 g. of the product of the Example as a tan solid.

후처리

  1. additionA mixture of 21.1 g
  2. temperatureat reflux temperature for 48 hours
  3. temperatureThe reaction mixture is cooled
  4. filtrationfiltered
  5. customThe solid is collected
  6. washwashed with water and air
  7. customdried
  8. customto yield 17.0 g

출처 및 근거

ORD 기록
ord-48403d4dbc804813a861d5cc9eae947e
출처 데이터셋
uspto-grants-1980_12
특허 번호
US04242515

연결된 노트

불러오는 중…