6-Acetyl-2-(4-chlorobutyryl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine → HCID 21471974, 화합물

HRID 1734086노트

반응식

HRID 1734086 반응식
[C:1]([N:4]1[CH2:9][CH2:8][C:7]2[CH:10]=[C:11]([C:13](=[O:18])[CH2:14][CH2:15][CH2:16]Cl)[S:12][C:6]=2[CH2:5]1)(=[O:3])[CH3:2].Cl.[F:20][C:21]1[CH:22]=[CH:23][C:24]2[C:28]([CH:29]3[CH2:34][CH2:33][NH:32][CH2:31][CH2:30]3)=[CH:27][S:26][C:25]=2[CH:35]=1>>[C:1]([N:4]1[CH2:9][CH2:8][C:7]2[CH:10]=[C:11]([C:13](=[O:18])[CH2:14][CH2:15][CH2:16][N:32]3[CH2:33][CH2:34][CH:29]([C:28]4[C:24]5[CH:23]=[CH:22][C:21]([F:20])=[CH:35][C:25]=5[S:26][CH:27]=4)[CH2:30][CH2:31]3)[S:12][C:6]=2[CH2:5]1)(=[O:3])[CH3:2]

참가 물질

3

반응물 2

HCID 214719026-Acetyl-2-(4-chlorobutyryl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridineHCID 226493344-(6-Fluorobenzo(b)thiophen-3-yl)piperidine hydrochloride

생성물 1

HCID 21471974HCID 21471974, 화합물

실험 절차

The reaction and procedure are conducted in a similar manner as in Example 24 using 6-acetyl-2-(4-chlorobutyryl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine and 4-(6-fluorobenzo(b)thiophen-3-yl)piperidine hydrochloride to give 6-acetyl-2-(4-(4-(6-fluorobenzo(b)thiophen-3-yl)piperidin-1-yl)butyryl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine.

후처리

  1. customThe reaction and procedure

출처 및 근거

ORD 기록
ord-28059d0a986a427ca91f80f519eca4bf
출처 데이터셋
uspto-grants-1996_07
특허 번호
US05532240

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