4-Bromo-3-methylisoxazol-5-amine → HCID 22998447, 화합물

반응식

[O:1]([C:8]1[CH:12]=[CH:11][S:10][C:9]=1[S:13](Cl)(=[O:15])=[O:14])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:17][C:18]1[O:22][N:21]=[C:20]([CH3:23])[C:19]=1[Br:24]>>[Br:24][C:19]1[C:20]([CH3:23])=[N:21][O:22][C:18]=1[NH:17][S:13]([C:9]1[S:10][CH:11]=[CH:12][C:8]=1[O:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)(=[O:15])=[O:14]

참가 물질

반응물 2

HCID 104875194-Bromo-3-methylisoxazol-5-amine

HCID 229984353-Phenoxythiophene-2-sulfonyl chloride

생성물 1

HCID 22998447HCID 22998447, 화합물

실험 절차

N-(4-bromo-3-methyl-5-isoxazolyl)-3-phenoxythiophene-2-sulfonamide was prepared from 3-phenoxythiophene-2-sulfonyl chloride and 5-amino-4-bromo-3-methylisoxazole using the method described in Example 1. The product was recrystallized from acetonitrile/H2O to give a solid m.p. 121-123° C., 61% yield.

후처리

customThe product was recrystallized from acetonitrile/H2O

출처 및 근거

ORD 기록: ord-17e03711e38f4f42b916aa0c58781398
출처 데이터셋: uspto-grants-1999_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05962490

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