2-Chloro-6-methylaniline → HCID 21836027, 화합물

HRID 1739624노트

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HRID 1739624 반응식
[F:1][C:2]1[C:15]2[C:14](=[O:16])[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[C:7](=[O:17])[C:6]=2[C:5]([F:18])=[C:4](F)[C:3]=1[F:20].[Cl:21][C:22]1[CH:28]=[CH:27][CH:26]=[C:25]([CH3:29])[C:23]=1[NH2:24]>>[Cl:21][C:22]1[CH:28]=[CH:27][CH:26]=[C:25]([CH3:29])[C:23]=1[NH:24][C:4]1[C:3]([F:20])=[C:2]([F:1])[C:15]2[C:14](=[O:16])[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[C:7](=[O:17])[C:6]=2[C:5]=1[F:18].[Cl:21][C:22]1[CH:28]=[CH:27][CH:26]=[C:25]([CH3:29])[C:23]=1[NH:24][C:4]1[C:3]([NH:24][C:23]2[C:25]([CH3:29])=[CH:26][CH:27]=[CH:28][C:22]=2[Cl:21])=[C:2]([F:1])[C:15]2[C:14](=[O:16])[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[C:7](=[O:17])[C:6]=2[C:5]=1[F:18]

참가 물질

4

반응물 2

HCID 68972-Chloro-6-methylaniline2회HCID 2833793HCID 2833793, 화합물

생성물 2

HCID 21836027HCID 21836027, 화합물HCID 21836034HCID 21836034, 화합물

실험 절차

2 g of 1,2,3,4-Tetrafluoroanthraquinone and 25 g of 2-chloro-6-methylaniline were charged in a 50 cc, four necked flask and then the reaction was carried out at 140° C. for about 6 hours. After completion of reaction, 2-chloro-6-methylaniline was distilled out from the reaction solution and a column purification thereof was effected to give rise to 1.07 g of 2-(2-chloro-6-methylanilino)-1,3,4-trifluoroanthraquinone (Dye 8') yield 37.3 mol %) and 0.78 g of 2,3-bis(2-chloro-6-methylanilino)-1,4-difluoroanthraquinone (Dye 21') (yield 24.2 mol %). The physical properties of Dye 8' and analytical values defining the compound are tabulated in Table 22 and the physical properties of Dye 21' and analytical values defining the compound are tabulated in Table 24.

후처리

  1. distillationwas distilled out from the reaction solution
  2. customa column purification

출처 및 근거

ORD 기록
ord-5f957c9ab9a8433fb3c0b800ba076677
출처 데이터셋
uspto-grants-1999_10
특허 번호
US05968688

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