참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Ethyl benzoylformate | HCID 15349 | — |
| 반응물 | 1-Benzyl-4-piperidylamine | HCID 415852 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | N-(1-benzyl-4-piperidinyl)phenyl-glyoxylic acid amide | HCID 11120838 | 81.4% |
반응 단계
Added to 4.28 g of ethyl phenylglyoxylate were 9.12 g of 4-amino-1-benzylpiperidine. The mixture was heated and stirred at 120° C. for 3 hours on an oil bath. Thereafter, ethanol formed was distilled off under reduced pressure, and the residue was purified by column chromatography on silica gel, thereby obtaining 6.3 g (yield: 81.4%) of N- (1-benzyl-4-piperidinyl)phenyl-glyoxylic acid amide.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05968956 |
|---|
| 출처 데이터셋 | uspto-grants-1999_10 |
|---|
| ORD ID | ord-8f477e3b0b734482a249820ee94a5696 |
|---|
| 출처 메모 | uspto-grants-1999_10 |
|---|
