Methyl 3-benzyloxycarbonylmethoxy-5-hydroxybenzoate → Methyl 3-carboxymethoxy-5-hydroxybenzoate

HRID 1740316노트

반응식

HRID 1740316 반응식
C([O:8][C:9]([CH2:11][O:12][C:13]1[CH:14]=[C:15]([CH:20]=[C:21]([OH:23])[CH:22]=1)[C:16]([O:18][CH3:19])=[O:17])=[O:10])C1C=CC=CC=1>[Pd].CO>[C:9]([CH2:11][O:12][C:13]1[CH:14]=[C:15]([CH:20]=[C:21]([OH:23])[CH:22]=1)[C:16]([O:18][CH3:19])=[O:17])([OH:10])=[O:8]

참가 물질

4

반응물 1

HCID 21838035Methyl 3-benzyloxycarbonylmethoxy-5-hydroxybenzoate

생성물 1

HCID 11253108Methyl 3-carboxymethoxy-5-hydroxybenzoate수율 103.5%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매

실험 절차

10% palladium on carbon (0.1 g) was added to a mixture of methyl 3-benzyloxycarbonylmethoxy-5-hydroxybenzoate (1 g) in methanol (20 ml) and the mixture was subjected to catalytic reduction at ambient temperature under atmospheric pressure. The catalyst was removed by filtration and the filtrate was evaporated in vacuo to give methyl 3-carboxymethoxy-5-hydroxybenzoate (0.74 g).

후처리

  1. customwas subjected to catalytic reduction at ambient temperature under atmospheric pressure
  2. customThe catalyst was removed by filtration
  3. customthe filtrate was evaporated in vacuo

출처 및 근거

ORD 기록
ord-ab7f2c9943814927bc5b195fdfcfcd25
출처 데이터셋
uspto-grants-1999_10
특허 번호
US05968985

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