1,4-Dioxane hydrochloride → HCID 21838655, 화합물
반응식
C([N:3]1[CH2:8][CH2:7][N:6]([CH2:9][CH2:10][O:11][CH3:12])[CH2:5][CH2:4]1)=O.[ClH:13].O1CCOCC1>CO>[ClH:13].[ClH:13].[CH3:12][O:11][CH2:10][CH2:9][N:6]1[CH2:7][CH2:8][NH:3][CH2:4][CH2:5]1참가 물질
4
실험 절차
To a solution of 57.2 g of 1-formyl-4-methoxyethylpiperazine in 100 mL of methanol was added dropwise 180 mL of 4N-hydrochloric acid/1,4-dioxane over 1.5 hours. The mixture was stirred at room temperature for 1 hour, and the resulting crystals were filtered, washed with isopropyl ether and dried in vacuo to give 68.8 g of the title compound.
후처리
- filtrationthe resulting crystals were filtered
- washwashed with isopropyl ether
- customdried in vacuo
출처 및 근거
- ORD 기록
- ord-0266294c143243be8e76115d5cdfc74c
- 출처 데이터셋
- uspto-grants-1999_10
- 특허 번호
- US05969138
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