Sarcosine → Creatine

HRID 1740539노트

반응식

[NH:1]([CH2:3][C:4]([OH:6])=[O:5])[CH3:2].Cl.CO[C:10](=[NH:12])[NH2:11]>>[O:5]=[C:4]([CH2:3][N:1]([C:10](=[NH:11])[NH2:12])[CH3:2])[OH:6]

참가 물질

반응물 2

HCID 1088Sarcosine

HCID 3083899Carbamimidic acid, methyl ester, hydrochloride (1:1)

생성물 1

HCID 586Creatine

실험 절차

The reaction of sarcosine with O-methylisourea hydrochloride, described by E. Schutte in Hoppe-Seylers Z. Physiol. Chemie 279 (1943) 52-59, affords creatine in a yield of only 21%.

출처 및 근거

ORD 기록: ord-1e8edc502378488c8e41b8272ade6bcc
출처 데이터셋: uspto-grants-1999_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05969182

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