tetrahydrofuran N-(13-benzyloxycarbonyltridecanoyloxy)succinimide → HCID 9928580, 화합물

HRID 1740662노트

반응식

HRID 1740662 반응식
C([O:8][C:9]([CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][C:23]([O:25][N:26]1[C:30](=[O:31])[CH2:29][CH2:28][C:27]1=[O:32])=[O:24])=[O:10])C1C=CC=CC=1.O1CCCC1>[C].[Pd]>[C:9]([CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][C:23]([O:25][N:26]1[C:30](=[O:31])[CH2:29][CH2:28][C:27]1=[O:32])=[O:24])([OH:10])=[O:8]

참가 물질

3

반응물 1

HCID 21832384tetrahydrofuran N-(13-benzyloxycarbonyltridecanoyloxy)succinimide

생성물 1

HCID 9928580HCID 9928580, 화합물수율 94%

시약·촉매·용매 1

HCID 178418390HCID 178418390, 화합물촉매

실험 절차

In 15 ml of tetrahydrofuran N-(13-benzyloxycarbonyltridecanoyloxy)succinimide (2.28 g, 5.12 mmoles) was dissolved. To the obtained solution, were added 228 mg of 10% palladium carbon and the mixture was stirred for 15 hours under an atmosphere of hydrogen. The reaction mixture was filtered and the filtrate was concentrated under reduced pressure. The residue was recrystallized from ethanol, to give N-(13-carboxytridecanoyloxy)succinimide (1.71 mg, 94%) having the following properties.

후처리

  1. filtrationThe reaction mixture was filtered
  2. concentrationthe filtrate was concentrated under reduced pressure
  3. customThe residue was recrystallized from ethanol

출처 및 근거

ORD 기록
ord-dd1f6ea7f0d8462098922d0e329ec454
출처 데이터셋
uspto-grants-1999_10
특허 번호
USRE036359

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