(2S,3S)-tert-Butyl 3-amino-2-phenylpiperidine-1-carboxylate → (2S,3S)-1-tert-Butoxycarbonyl-3-[(7-methoxy-1,2,4,5-tetrahydroimidazo[1,2-a]quinolin-8-yl)methyl]amino-2-phenylpiperidine

반응식

[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[CH:13]=O)[N:9]1[CH2:15][CH2:16][N:17]=[C:8]1[CH2:7][CH2:6]2.[NH2:18][C@H:19]1[CH2:24][CH2:23][CH2:22][N:21]([C:25]([O:27][C:28]([CH3:31])([CH3:30])[CH3:29])=[O:26])[C@H:20]1[C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1.C(OC(N1CCC[C@H](NCC2C=C3C(CCC4N3N=NN=4)=CC=2OC)[C@@H]1C1C=CC=CC=1)=O)(C)(C)C>>[C:28]([O:27][C:25]([N:21]1[CH2:22][CH2:23][CH2:24][C@H:19]([NH:18][CH2:13][C:12]2[CH:11]=[C:10]3[C:5]([CH2:6][CH2:7][C:8]4[N:9]3[CH2:15][CH2:16][N:17]=4)=[CH:4][C:3]=2[O:2][CH3:1])[C@@H:20]1[C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1)=[O:26])([CH3:31])([CH3:29])[CH3:30]