Sulfuric Acid → HCID 21835783, 화합물

HRID 1741347노트

반응식

HRID 1741347 반응식
[C:1]([CH:4]=[N:5][C:6]1[C:7](=[CH:11][CH:12]=[C:13]([Cl:15])[CH:14]=1)[C:8]([OH:10])=[O:9])([OH:3])=[O:2].S(=O)(=O)(O)O.[CH:21](O)([CH3:23])[CH3:22]>>[C:1]([CH:4]=[N:5][C:6]1[C:7](=[CH:11][CH:12]=[C:13]([Cl:15])[CH:14]=1)[C:8]([OH:10])=[O:9])([O:3][CH:21]([CH3:23])[CH3:22])=[O:2]

참가 물질

4

반응물 3

HCID 1118Sulfuric AcidHCID 3776IsopropanolHCID 19597249HCID 19597249, 화합물

생성물 1

HCID 21835783HCID 21835783, 화합물수율 78%

실험 절차

5 g (21.8 mmol) of N-carboxymethylene-4-chloro-anthranilic acid are suspended in 50 ml of isopropanol, and 222 mg (2.3 mmol) of sulfuric acid are added. The mixture is heated under reflux for 8.25 hours. It is then cooled to room temperature and the product which has precipitated out is washed with petroleum ether and dried. 4.6 g (16.9 mmol; 78%) of N-carboisopropoxymethylene-4-chloro-anthranilic acid are obtained.

후처리

  1. temperatureThe mixture is heated
  2. temperatureunder reflux for 8.25 hours
  3. customthe product which has precipitated out
  4. washis washed with petroleum ether
  5. customdried

출처 및 근거

ORD 기록
ord-43127324cf9641438ece1bafff033e7a
출처 데이터셋
uspto-grants-1999_10
특허 번호
US05973189

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