Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethylamine → Benzyl [2-(dimethylcarbamoyl)ethyl]carbamate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethylamine | HCID 674 | — |
| 반응물 | N-Benzyloxycarbonyl-beta-alanine | HCID 75313 | — |
| 반응물 | 1-Hydroxybenzotriazole | HCID 75771 | — |
| 반응물 | 1-(Dimethylaminopropyl)-3-ethylcarbodiimide 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride | HCID 86630846 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | Benzyl [2-(dimethylcarbamoyl)ethyl]carbamate | HCID 19971000 | — |
반응 단계
3-[N-(benzyloxycarbonyl)amino]propionic acid (0.70 g, 3.14 mmol) was dissolved in N,N-dimethylformamide (15 ml), and 1-(dimethylaminopropyl)-3-ethylcarbodiimide 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (0.60 g, 3.13 mmol), 1-hydroxybenzotriazole (0.48 g, 3.13 mmol) and dimethylamine (2.0 M tetrahydrofuran solution, 2.40 ml, 4.80 mmol) were added, followed by stirring at room temperature for 3 days.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07737166B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-c7d6e340cfde438e99b3fd01fbe9dda4 |
| 출처 메모 | uspto-grants-2010_06 |