Ethyl isocyanate → 1-(3-Fluorobenzoyl)-4-ethyl semicarbazide

HRID 1741862

반응식

HRID 1741862 반응식
[F:1][C:2]1[CH:3]=[C:4]([CH:9]=[CH:10][CH:11]=1)[C:5]([NH:7][NH2:8])=[O:6].[CH2:12]([N:14]=[C:15]=[O:16])[CH3:13]>O1CCCC1>[F:1][C:2]1[CH:3]=[C:4]([CH:9]=[CH:10][CH:11]=1)[C:5]([NH:7][NH:8][C:15]([NH:14][CH2:12][CH3:13])=[O:16])=[O:6]

참가 물질

4

반응물 2

HCID 8022Ethyl isocyanateHCID 3516403-Fluorobenzohydrazide

생성물 1

HCID 190109271-(3-Fluorobenzoyl)-4-ethyl semicarbazide

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

To a solution of 3-fluorobenzhydrazide (5.0 g, 0.033 mol) in tetrahydrofuran (100 mL) was added ethyl isocyanate (2.6 g, 0.036 mol) at room temperature. After stirring for 24 hr, the resultant precipitate was collected by suction-filtration to give 1-(3-fluorobenzoyl)-4-ethyl semicarbazide in quantitative yield.

후처리

  1. filtrationthe resultant precipitate was collected by suction-filtration

출처 및 근거

ORD 기록
ord-60e167f32a3f43108cdec2a2df8fa259
출처 데이터셋
uspto-grants-1994_08
특허 번호
US05334726

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