Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Tramadol → Desmetramadol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Tramadol | HCID 33741 | — |
| 반응물 | (-)-(S,S)-trans-Tramadol | HCID 667511 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | Desmetramadol | HCID 9838803 | — |
반응 단계
To prepare the (+) enantiomer of the title compound, the reaction was run under the same conditions except that (+)-tramadol as the free base was used instead of the (-)-tramadol to yield 2.8 g of the (+) enantiomer of O-desmethyl tramadol (mp. 242°-3° C.) [α]D25 =+32.2 (C=1, EtOH).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05336691 |
| 출처 데이터셋 | uspto-grants-1994_08 |
| ORD ID | ord-6fa8701eeca94b1196e05d5011e511a9 |
| 출처 메모 | uspto-grants-1994_08 |