Ammonia → Lodenosine

HRID 1742052노트

반응식

HRID 1742052 반응식
Cl[C:2]1[N:10]=[CH:9][N:8]=[C:7]2[C:3]=1[N:4]=[CH:5][N:6]2[C@@H:11]1[O:15][C@H:14]([CH2:16][OH:17])[CH2:13][C@@H:12]1[F:18].[NH3:19]>>[NH2:19][C:2]1[N:10]=[CH:9][N:8]=[C:7]2[C:3]=1[N:4]=[CH:5][N:6]2[C@@H:11]1[O:15][C@H:14]([CH2:16][OH:17])[CH2:13][C@@H:12]1[F:18]

참가 물질

3

반응물 2

HCID 222AmmoniaHCID 3655276-Chloro-9-(2,3-dideoxy-2-fluoropentofuranosyl)-9H-purine

생성물 1

HCID 72180Lodenosine

실험 절차

A solution of 6-chloro-9-(2,3-dideoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine (16 mg, 0.059 mmol) in saturated methanolic ammonia (5 ml) was sealed in a glass tube under an atmosphere of ammonia.

출처 및 근거

ORD 기록
ord-b1469f6d23e347688ba8ea5d7b5fc507
출처 데이터셋
uspto-grants-1994_08
특허 번호
US05336764

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