Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Fluoroethyl bromide → 2-(2-Fluoroethyl)-2-(4-methoxybenzyl)malononitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Fluoroethyl bromide | HCID 12982 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | 2-(4-Methoxybenzyl)malononitrile | HCID 2764141 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 2-(2-Fluoroethyl)-2-(4-methoxybenzyl)malononitrile | HCID 22234967 | 50.3% |
반응 단계
Using 0.37 g of (4-methoxybenzyl)malononitrile, 5 ml of N,N-dimethylformamide, 0.12 g of sodium hydride (60% in oil), and 0.25 g of 1-bromo-2-fluoroethane, and according to the process described in the Production Example 1, there was obtained 0.23 g of 2-(2-fluoroethyl)-2-(4-methoxybenzyl)malononitrile (the present compound (52)).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07011838B2 |
| 출처 데이터셋 | uspto-grants-2006_03 |
| ORD ID | ord-005d0d1113074435aeaec4eced442c4a |
| 출처 메모 | uspto-grants-2006_03 |