Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium hydride → 2-(4-Methoxybenzyl)-2-(3,3,3-trifluoropropyl)malononitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | 3-Bromo-1,1,1-trifluoropropane | HCID 2725114 | — |
| 반응물 | 2-(4-Methoxybenzyl)malononitrile | HCID 2764141 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 2-(4-Methoxybenzyl)-2-(3,3,3-trifluoropropyl)malononitrile | HCID 22235014 | 27.7% |
반응 단계
Using 0.39 g of 2-(4-methoxybenzyl)malononitrile, 5 ml of N,N-dimethylformamide, 0.12 g of sodium hydride (60% in oil), and 0.34 g of 1-bromo-3,3,3-trifluoropropane, and according to the process described in the Production Example 1, there was obtained 0.15 g of 2-(4-methoxybenzyl)-2-(3,3,3-trifluoropropyl)malononitrile (the present compound (89)).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07011838B2 |
| 출처 데이터셋 | uspto-grants-2006_03 |
| ORD ID | ord-4f1d0aa6a168436cbc40ac0b2139b8df |
| 출처 메모 | uspto-grants-2006_03 |