2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine → 6-Acetyl-9-chloro-3-fluoro-5,6-dihydro-2-(6-methoxy-3-pyridinyl) pyrido[3,2-c][1]benzazocine

반응식

[C:1]([CH3:2])(=[O:3])[N:4]1[CH2:5][c:6]2[c:7]([n:17][c:18]([Cl:22])[c:19]([F:21])[cH:20]2)[CH:8]=[CH:9][c:10]2[c:11]1[cH:12][cH:13][c:14]([Cl:16])[cH:15]2.[C:40]([N:41]1[c:42]2[cH:43][cH:44][cH:45][cH:46][c:47]2[CH:48]=[CH:49][c:50]2[n:51][c:52](-[c:53]3[cH:54][n:55][c:56]([O:57][CH3:58])[cH:59][cH:60]3)[c:61]([F:62])[cH:63][c:64]2[CH2:65]1)(=[O:66])[CH3:67].[CH3:23][O:24][c:25]1[n:26][cH:27][c:28]([B:31]2[O:32][C:33]([CH3:34])([CH3:35])[C:36]([CH3:37])([CH3:38])[O:39]2)[cH:29][cH:30]1>>[C:1]([CH3:2])(=[O:3])[N:4]1[CH2:5][c:6]2[c:7]([n:17][c:18](-[c:28]3[cH:27][n:26][c:25]([O:24][CH3:23])[cH:30][cH:29]3)[c:19]([F:21])[cH:20]2)[CH:8]=[CH:9][c:10]2[c:11]1[cH:12][cH:13][c:14]([Cl:16])[cH:15]2