Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pyridine → 1-(4-Chlorophenyl)-N-(4-chloro-3-nitrophenyl)-5-methylpyrazole-4-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pyridine | HCID 1049 | — |
| 반응물 | 4-Chloro-3-nitroaniline | HCID 12477 | — |
| 반응물 | 1-(4-chlorophenyl)-5-methyl-1H-pyrazole-4-carbonyl chloride | HCID 2776128 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 1-(4-Chlorophenyl)-N-(4-chloro-3-nitrophenyl)-5-methylpyrazole-4-carboxamide | HCID 22228091 | 92.6% |
반응 단계
1-(4-Chlorophenyl)-5-methylpyrazole-4-carboxylic chloride (1.7 g) was added to a pyridine solution of 4-chloro-3-nitroaniline (1 g) and the mixture was stirred at room temperature for 2 h. After the reaction, water was added and the precipitated solid was collected by filtration to give the title compound (2.1 g), melting point:221–225° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07015218B1 |
| 출처 데이터셋 | uspto-grants-2006_03 |
| ORD ID | ord-0694f807d2394b3ca2ffb8affed3564d |
| 출처 메모 | uspto-grants-2006_03 |