Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(3-chlorophenyl)-5-methyl-1H-pyrazole-4-carboxylic acid → 1-(3-Chlorophenyl)-N-[3-cyano-4-(4-morpholinopiperidin-1-yl)phenyl]-5-methylpyrazole-4-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(3-chlorophenyl)-5-methyl-1H-pyrazole-4-carboxylic acid | HCID 4423672 | — |
| 반응물 | 5-Amino-2-(4-morpholinopiperidin-1-yl)benzonitrile | HCID 21942389 | — |
| 생성물 | 1-(3-Chlorophenyl)-N-[3-cyano-4-(4-morpholinopiperidin-1-yl)phenyl]-5-methylpyrazole-4-carboxamide | HCID 22227854 | 23.6% |
반응 단계
By the reaction and treatment in the same manner as in Example 64 using 1-(3-chlorophenyl)-5-methylpyrazole-4-carboxylic acid (2.0 g) and 5-amino-2-(4-morpholinopiperidin-1-yl)benzonitrile (2.4 g), the title compound (1.0 g) was obtained, melting point: 210° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07015218B1 |
| 출처 데이터셋 | uspto-grants-2006_03 |
| ORD ID | ord-e091ba7db13e4270a2132204a7dcd01b |
| 출처 메모 | uspto-grants-2006_03 |