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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1744660생성일: 2026년 10월 26일

1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxylic acid → N-{3-Cyano-4-[4-(3,4,5,6-tetrahydro-2H-pyran-4-yl)piperazin-1-yl]phenyl}-1-(4-fluorophenyl)-5-methylpyrazole-4-carboxamide

https://huagongshe.com/reaction/1744660

반응식

참여 물질

역할이름HCID투입량
반응물1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxylic acidHCID 4270263—
반응물5-amino-2-[4-(3,4,5,6-tetrahydro-2H-pyran-4-yl)piperazin-1-yl]benzonitrileHCID 21942323—
생성물N-{3-Cyano-4-[4-(3,4,5,6-tetrahydro-2H-pyran-4-yl)piperazin-1-yl]phenyl}-1-(4-fluorophenyl)-5-methylpyrazole-4-carboxamideHCID 2222801545.1%

반응 단계

By the reaction and treatment in the same manner as in Example 64 using 1-(4-fluorophenyl)-5-methylpyrazole-4-carboxylic acid (0.6 g) and 5-amino-2-[4-(3,4,5,6-tetrahydro-2H-pyran-4-yl)piperazin-1-yl]benzonitrile (0.8 g), the title compound (0.6 g) was obtained, melting point: 240° C.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07015218B1
출처 데이터셋uspto-grants-2006_03
ORD IDord-fb6a9eb049174fdb9f802953b46b5212
출처 메모uspto-grants-2006_03