3-Chloropyridine → HCID 44243553, 화합물

반응식

Cc1noc(C)c1B1OC(C)(C)C(C)(C)O1.Clc1cccnc1>C1CCC2=NCCCN2CC1.C1CCOC1.CC(C)(C)P(C(C)(C)C)C(C)(C)C.CS(=O)(=O)[O][Pd][c]1ccccc1-c1ccccc1N.O>Cc1noc(C)c1-c1cccnc1

참가 물질

반응 조건

온도: 110 °C

후처리

additionAs soon as the slug leaves the reactor and is detected at PS2,a quench solution volume equal to the reaction slug volume(prepared slug volume + base injection volume) is injected into the reaction slug

출처 및 근거

ORD 기록: ord-1b409b63e8a94538a8f8ecdc25b8086d
출처 데이터셋: Reizman Suzuki Cross-Coupling
DOI: 10.1039/C6RE00153J
원본 링크: 출처 보기

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불러오는 중…

참가 물질

반응물 2

HCID 122873-Chloropyridine

HCID 27586563,5-Dimethylisoxazole-4-boronic acid pinacol ester

생성물 1

HCID 44243553HCID 44243553, 화합물수율 5.7%

시약·촉매·용매 7

HCID 811841,8-Diazabicyclo(5.4.0)undec-7-ene시약

HCID 178454885HCID 178454885, 화합물촉매

HCID 962Water용매

HCID 8028Tetrahydrofuran용매5회

HCID 180Acetone후처리

HCID 931Naphthalene내부 표준

HCID 962Water후처리

반응 조건

온도: 110 °C

후처리

additionAs soon as the slug leaves the reactor and is detected at PS2,a quench solution volume equal to the reaction slug volume(prepared slug volume + base injection volume) is injected into the reaction slug

출처 및 근거

ORD 기록: ord-1b409b63e8a94538a8f8ecdc25b8086d
출처 데이터셋: Reizman Suzuki Cross-Coupling
DOI: 10.1039/C6RE00153J
원본 링크: 출처 보기

반응 노트

불러오는 중…