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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1746760생성일: 2026년 10월 26일

N-(2-Methoxyethyl)isopropylamine → N-1H-indazol-5-yl-6-[isopropyl(2-methoxyethyl)amino]pyrimidine-4-carboxamide

https://huagongshe.com/reaction/1746760

반응식

참여 물질

역할이름HCID투입량
반응물N-(2-Methoxyethyl)isopropylamineHCID 551575—
반응물6-chloro-N-1H-indazol-5-ylpyrimidine-4-carboxamideHCID 59446880—
생성물N-1H-indazol-5-yl-6-[isopropyl(2-methoxyethyl)amino]pyrimidine-4-carboxamideHCID 25182931—

반응 단계

Following the general method as outlined in Example 20, starting from 6-chloro-pyrimidine-4-carboxylic acid (1H-indazol-5-yl)-amide (Intermediate 16) and N-(2-methoxyethyl)isopropylamine (ABCR), the title compound was obtained as a yellow solid after purification by column chromatography (silica) eluting with cyclohexane containing increasing amounts of EtOAc.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09150519B2
출처 데이터셋uspto-grants-2015_10
ORD IDord-6bec25e0d9da403c98bd50b026325df9
출처 메모uspto-grants-2015_10