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llms.txt · MCP 가이드개인정보처리방침 · 이용약관 · 지원v1.8.0
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(2S)-2-amino-3-{[(5-chloro-2-hydroxy-3-sulfophenyl)carbamoyl]amino}propanoic acid → (2S)-2-amino-3-{[(2-hydroxy-3-sulfophenyl)carbamoyl]amino}propanoic acid

HRID 1746830
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인쇄 미리보기

반응식

HRID 1746830 반응식
[NH2:1][C@@H:2]([CH2:6][NH:7][C:8](=[O:22])[NH:9][C:10]1[CH:15]=[C:14](Cl)[CH:13]=[C:12]([S:17]([OH:20])(=[O:19])=[O:18])[C:11]=1[OH:21])[C:3]([OH:5])=[O:4].[H][H]>O.CO.[Pd]>[NH2:1][C@@H:2]([CH2:6][NH:7][C:8](=[O:22])[NH:9][C:10]1[CH:15]=[CH:14][CH:13]=[C:12]([S:17]([OH:20])(=[O:18])=[O:19])[C:11]=1[OH:21])[C:3]([OH:5])=[O:4]
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

6

반응물 2

HCID 53377991(2S)-2-amino-3-{[(5-chloro-2-hydroxy-3-sulfophenyl)carbamoyl]amino}propanoic acidHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 86679034(2S)-2-amino-3-{[(2-hydroxy-3-sulfophenyl)carbamoyl]amino}propanoic acid

시약·촉매·용매 3

HCID 23938Palladium촉매HCID 887Methanol용매
HCID 962
Water
용매

실험 절차

The compound obtained in Example 6 was dissolved in water and methanol, to which a catalyst amount of Pd/C was added, and the resultant was stirred for three days in a hydrogen atmosphere. After filtrating the catalyst, the solvent was distilled away, and the resultant was purified using purification step A to obtain the title compound.

후처리

  1. filtrationAfter filtrating the catalyst
  2. distillationthe solvent was distilled away
  3. customthe resultant was purified
  4. custompurification step A

출처 및 근거

ORD 기록
ord-b4eb94f8baa64c72a27625fec48c7d4a
출처 데이터셋
uspto-grants-2015_10
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US09150505B2

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