HCID 76183230, 화합물 → Methyl 4,4-difluoro-3-oxobutanoate
반응식
[F:1][CH:2]([F:10])[C:3]([OH:9])=[CH:4][C:5]([O:7][CH3:8])=[O:6]>CO>[F:1][CH:2]([F:10])[C:3](=[O:9])[CH2:4][C:5]([O:7][CH3:8])=[O:6]참가 물질
3
실험 절차
The procedure of Example 4 was repeated using methanol instead of ethanol. After distillation the methyl ester was obtained as a colorless liquid. According to the 1H NMR data the product was a tautomeric mixture of ca. 60% keto form and ca. 40% enol form (methyl 4,4-difluoro-3-hydroxybut-2-enoate).
후처리
- distillationAfter distillation the methyl ester
- customwas obtained as a colorless liquid
출처 및 근거
- ORD 기록
- ord-5ca2312bf468435da2dfd0d085194da8
- 출처 데이터셋
- uspto-grants-2015_10
- 특허 번호
- US09156771B2
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