1-Benzyl-N-cyclopropylpiperidin-4-amine → N-(1-benzylpiperidine-4-yl)-2-(6-chloropyridazine-3-yloxy)-N-cyclopropylacetamide

HRID 1749323

반응식

HRID 1749323 반응식
[Cl:1][C:2]1[N:7]=[N:6][C:5]([O:8][CH2:9][C:10]([O:12]CC)=O)=[CH:4][CH:3]=1.[CH2:15]([N:22]1[CH2:27][CH2:26][CH:25]([NH:28][CH:29]2[CH2:31][CH2:30]2)[CH2:24][CH2:23]1)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[CH2:15]([N:22]1[CH2:23][CH2:24][CH:25]([N:28]([CH:29]2[CH2:30][CH2:31]2)[C:10](=[O:12])[CH2:9][O:8][C:5]2[N:6]=[N:7][C:2]([Cl:1])=[CH:3][CH:4]=2)[CH2:26][CH2:27]1)[C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1

참가 물질

3

반응물 2

HCID 27354811-Benzyl-N-cyclopropylpiperidin-4-amineHCID 86641965Ethyl 2-(6-chloropyridazine-3-yloxy)acetate

생성물 1

HCID 25121189N-(1-benzylpiperidine-4-yl)-2-(6-chloropyridazine-3-yloxy)-N-cyclopropylacetamide

실험 절차

The title compound was synthesized from ethyl 2-(6-chloropyridazine-3-yloxy)acetate and 1-benzyl N-cyclopropylpiperidine-4-amine in the same manner as in Example 104.

출처 및 근거

ORD 기록
ord-e59f87eaa8fc409088695395ca88ae16
출처 데이터셋
uspto-grants-2015_10
특허 번호
US09156817B2

연결된 노트

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