Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,5-dimethyl-1H-pyrazol-4-amine → 4-Bromo-2,6-dichloro-N-(1,5-dimethyl-1H-pyrazol-4-yl)-benzenesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,5-dimethyl-1H-pyrazol-4-amine | HCID 573813 | — |
| 반응물 | 4-Bromo-2,6-dichlorobenzene-1-sulfonyl chloride | HCID 2737466 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | 4-Bromo-2,6-dichloro-N-(1,5-dimethyl-1H-pyrazol-4-yl)-benzenesulfonamide | HCID 58561405 | 64.3% |
반응 단계
Prepared from 4-bromo-2,6-dichlorobenzenesulfonyl chloride (500 mg, 1.54 mmol) and 4-amino-1,5-dimethyl-1H-pyrazole (172 mg, 1.55 mmol) in pyridine (3 ml) according to the method of intermediate 1, to give the title compound as a cream solid (392 mg, 0.99 mmol, 64%). δH (D-6 DMSO, 300K) 9.91 (1H, s), 7.97 (2H, s), 3.64 (3H, s), 2.04 (3H, s). m/z (ES+, 70V) 399.9 (MH+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09156811B2 |
| 출처 데이터셋 | uspto-grants-2015_10 |
| ORD ID | ord-a95dfe19bb7846d89faa480e860fd947 |
| 출처 메모 | uspto-grants-2015_10 |