Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(1-Ethyl-propylamino)-3-nitro-benzoic acid methyl ester → Methyl 3-amino-4-(pentan-3-ylamino)benzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(1-Ethyl-propylamino)-3-nitro-benzoic acid methyl ester | HCID 85998571 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | Methyl 3-amino-4-(pentan-3-ylamino)benzoate | HCID 61311526 | — |
반응 단계
7.00 g of 4-(1-Ethyl-propylamino)-3-nitro-benzoic acid methyl ester were dissolved in 70 ml ethanol, 0.35 g of palladium on carbon (10%) were added and the mixture was hydrogenated at 5 bar for 4 h. The catalyst was removed by filtration over celite, the filtrate was concentrated and after crystallization from diethylether 5.00 g (65%) of 3-Amino-4-(1-ethyl-propylamino)-benzoic acid methyl ester were obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09156796B2 |
| 출처 데이터셋 | uspto-grants-2015_10 |
| ORD ID | ord-56c220aef3724603bce099bbb4fd0797 |
| 출처 메모 | uspto-grants-2015_10 |