반응식
[I:1][C:2]1[O:3][CH:4]=[CH:5][C:6]=1[C:7]([OH:9])=O.S(Cl)([Cl:12])=O>>[I:1][C:2]1[O:3][CH:4]=[CH:5][C:6]=1[C:7]([Cl:12])=[O:9]참가 물질
3
반응 조건
- 온도
- 70 °C
실험 절차
To 2-iodofuran-3-carboxylic acid (6.21 g, 26.1 mmol) was added thionyl chloride (20 ml, 274 mmol). The solution was heated while stirring to 70° C. for 5 h. The mixture was reduced in vacuo and the residue azeotroped with toluene (2×30 ml) to afford the crude title compound (6.69 g, 100%), which was used in the next step without further purification.
후처리
- temperatureThe solution was heated
- customthe residue azeotroped with toluene (2×30 ml)
출처 및 근거
- ORD 기록
- ord-beceb651d40c4d8eaf4e2b67f13b6f90
- 출처 데이터셋
- uspto-grants-2015_10
- 특허 번호
- US09156853B2
연결된 노트
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