2(2H-Perfluoro-2-propyl)acetic acid → HCID 86721215, 화합물
반응식
Cl.[C:2]([N:6]1[C:10]([C:11]2[CH:16]=[CH:15][C:14]([F:17])=[CH:13][CH:12]=2)=[C:9]([C:18]2[S:19][CH:20]=[C:21]([CH:23]3[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]3)[N:22]=2)[CH:8]=[N:7]1)([CH3:5])([CH3:4])[CH3:3].[F:29][C:30]([F:41])([F:40])[CH:31]([C:36]([F:39])([F:38])[F:37])[CH2:32][C:33](O)=[O:34]>>[C:2]([N:6]1[C:10]([C:11]2[CH:16]=[CH:15][C:14]([F:17])=[CH:13][CH:12]=2)=[C:9]([C:18]2[S:19][CH:20]=[C:21]([CH:23]3[CH2:24][CH2:25][N:26]([C:33](=[O:34])[CH2:32][CH:31]([C:30]([F:40])([F:41])[F:29])[C:36]([F:37])([F:39])[F:38])[CH2:27][CH2:28]3)[N:22]=2)[CH:8]=[N:7]1)([CH3:5])([CH3:3])[CH3:4]참가 물질
3
실험 절차
Using 4-{2-[1-tert-butyl-5-(4-fluorophenyl)-1H-pyrazol-4-yl]-1,3-thiazol-4-yl}piperidine monohydrochloride and 4,4,4-trifluoro-3-(trifluoromethyl)butyric acid and by reaction and purification in the same manner as in the method described in Example 1, step 7, the title compound was obtained.
후처리
- customby reaction and purification in the same manner as in the method
출처 및 근거
- ORD 기록
- ord-e54151afd5004f18b169cfd4556b04de
- 출처 데이터셋
- uspto-grants-2015_10
- DOI