2-(Pyrimidin-2-yl)benzoic acid → N-[(1S,2S)-2-{[3-Ethyl-5-(trifluoromethyl)pyrazin-2-yl]amino}cyclopentyl]-2-(pyrimidin-2-yl)benzamide

반응식

[CH2:1]([C:3]1[C:4]([NH:13][C@H:14]2[CH2:18][CH2:17][CH2:16][C@@H:15]2[NH:19][C:20](=[O:33])[C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=2[C:27]2ON=[C:29]([CH3:32])[N:28]=2)=[N:5][CH:6]=[C:7]([C:9]([F:12])([F:11])[F:10])[N:8]=1)[CH3:2].Cl.C(C1[C:38](N[C@H]2CCC[C@@H]2N)=[N:39]C=C(C(F)(F)F)N=1)C.N1C=CC=NC=1C1C=CC=CC=1C(O)=O>>[CH2:1]([C:3]1[C:4]([NH:13][C@H:14]2[CH2:18][CH2:17][CH2:16][C@@H:15]2[NH:19][C:20](=[O:33])[C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=2[C:27]2[N:39]=[CH:38][CH:32]=[CH:29][N:28]=2)=[N:5][CH:6]=[C:7]([C:9]([F:11])([F:10])[F:12])[N:8]=1)[CH3:2]