Potassium Carbonate → (S)-1-((S)-2-(5-(4-(6-(2-((S)-1-((R)-2-(methoxycarbonylamino)-2-phenylacetyl)pyrrolidin-2-yl)-1H-imidazol-5-yl)naphthalen-2-yl)phenyl)-1H-imidazol-2-yl)thiazolidin-3-yl)-3-methyl-1-oxobutan-2-ylcarbamic acid methyl ester

반응식

Br[C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH:8]=[C:7]([C:12]1[NH:16][C:15]([C@@H:17]3[CH2:21][CH2:20][CH2:19][N:18]3[C:22](=[O:35])[C@H:23]([NH:30][C:31](=[O:34])[O:32][CH3:33])[C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)=[N:14][CH:13]=1)[CH:6]=[CH:5]2.CC(C)[C@H:38]([NH:66][C:67](=[O:70])[O:68][CH3:69])[C:39](=[O:65])[N:40]1[CH2:44][CH2:43][S:42][C@H:41]1[C:45]1[NH:46][C:47]([C:50]2[CH:55]=[CH:54][C:53](B3OC(C)(C)C(C)(C)O3)=[CH:52][CH:51]=2)=[CH:48][N:49]=1.[C:72]([O-])([O-])=O.[K+].[K+].O1[CH2:83][CH2:82]OCC1>C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.Cl[Pd]Cl.[Fe+2]>[CH3:69][O:68][C:67](=[O:70])[NH:66][C@@H:38]([CH:82]([CH3:83])[CH3:72])[C:39]([N:40]1[CH2:44][CH2:43][S:42][C@H:41]1[C:45]1[NH:46][C:47]([C:50]2[CH:51]=[CH:52][C:53]([C:2]3[CH:11]=[CH:10][C:9]4[C:4](=[CH:5][CH:6]=[C:7]([C:12]5[NH:16][C:15]([C@@H:17]6[CH2:21][CH2:20][CH2:19][N:18]6[C:22](=[O:35])[C@H:23]([NH:30][C:31]([O:32][CH3:33])=[O:34])[C:24]6[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=6)=[N:14][CH:13]=5)[CH:8]=4)[CH:3]=3)=[CH:54][CH:55]=2)=[CH:48][N:49]=1)=[O:65]