2-(4-Chlorophenoxy)ethanol → 5,7-Diethyl-2-[-2-(4-chlorophenoxy)ethoxy]-[1,2,4]triazolo[1,5-a]pyrimidine

HRID 1752800노트

반응식

HRID 1752800 반응식
CS([C:5]1[N:17]=[C:8]2[N:9]=[C:10]([CH2:15][CH3:16])[CH:11]=[C:12]([CH2:13][CH3:14])[N:7]2[N:6]=1)(=O)=O.[Cl:18][C:19]1[CH:28]=[CH:27][C:22]([O:23][CH2:24][CH2:25][OH:26])=[CH:21][CH:20]=1>>[CH2:15]([C:10]1[CH:11]=[C:12]([CH2:13][CH3:14])[N:7]2[N:6]=[C:5]([O:26][CH2:25][CH2:24][O:23][C:22]3[CH:27]=[CH:28][C:19]([Cl:18])=[CH:20][CH:21]=3)[N:17]=[C:8]2[N:9]=1)[CH3:16]

참가 물질

3

반응물 2

HCID 159072-(4-Chlorophenoxy)ethanolHCID 867193202-Methanesulfonyl-5,7-diethyl-[1,2,4]triazolo[1,5-a]pyrimidine

생성물 1

HCID 766847945,7-Diethyl-2-[-2-(4-chlorophenoxy)ethoxy]-[1,2,4]triazolo[1,5-a]pyrimidine수율 80%

실험 절차

The title compound was prepared according to the experimentals described for Example 14 above from 2-methanesulfonyl-5,7-diethyl-[1,2,4]triazolo[1,5-a]pyrimidine and 2-(4-chlorophenoxy)ethan-1-ol in 80% yield. EM (calc.): 346.1; MS (ESI) m/e: 347.3 (M+H)+.

출처 및 근거

ORD 기록
ord-1a9be86d3f074314be306d62ca54be26
출처 데이터셋
uspto-grants-2015_10
특허 번호
US09163027B2

반응 노트

불러오는 중…