4-Chloroanisole → 5'-Chloro-3,5-difluoro-2'-methoxybiphenyl-4-yl phenyl sulfone

반응식

[BH:19]([OH:20])[OH:21].[Cl:22][c:23]1[cH:24][cH:25][c:26]([O:29][CH3:30])[cH:27][cH:28]1.[c:1]1([S:7](=[O:8])(=[O:9])[c:10]2[c:11]([F:18])[cH:12][c:13]([Br:17])[cH:14][c:15]2[F:16])[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([S:7](=[O:8])(=[O:9])[c:10]2[c:11]([F:18])[cH:12][c:13](-[c:25]3[cH:24][c:23]([Cl:22])[cH:28][cH:27][c:26]3[O:29][CH3:30])[cH:14][c:15]2[F:16])[cH:2][cH:3][cH:4][cH:5][cH:6]1

참가 물질

반응물 3

HCID 121674-Chloroanisole

HCID 61668Boronic Acid

HCID 684362694-Bromo-2,6-difluorophenyl phenyl sulfone

생성물 1

HCID 672400705'-Chloro-3,5-difluoro-2'-methoxybiphenyl-4-yl phenyl sulfone

출처 및 근거

ORD 기록: ord-add91ff03a394b41a4f919933e4ecd5f
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…