HCID 86257708, 화합물 → 1-(4-fluorophenyl)-1H-pyrazol-4-amine
반응식
[F:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH:12]=[C:11]([N+:13]([O-])=O)[CH:10]=[N:9]2)=[CH:4][CH:3]=1>CCO.[Pd]>[F:1][C:2]1[CH:3]=[CH:4][C:5]([N:8]2[CH:12]=[C:11]([NH2:13])[CH:10]=[N:9]2)=[CH:6][CH:7]=1참가 물질
4
실험 절차
A mixture of 1-(4-fluorophenyl)-4-nitropyrazole (0.820 g, 3.96 mmol) and 10% Pd/C (0.133 g, 50% wet by wt) in EtOH (50 mL) was fitted onto a Parr apparatus and agitated under H2 at 40 psi for 40 min. The reaction mixture was then filtered through filter paper. The filtrate was collected and concentrated in vacuo to give 1-(4-fluorophenyl)pyrazol-4-amine as an oil (0.675 g, 96%).
후처리
- customwas fitted onto a Parr apparatus
- filtrationThe reaction mixture was then filtered
- filtrationthrough filter paper
- customThe filtrate was collected
- concentrationconcentrated in vacuo
출처 및 근거
- ORD 기록
- ord-a18390c029154e59af9a3eb968c86735
- 출처 데이터셋
- uspto-grants-2015_10
- 특허 번호
- US09169248B2
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