Diethyl Ether → 3-Methyl-7-(2-phenylethyl)pyrrolo[2,3-b]pyridine hydrobromide
반응식
[CH3:1][C:2]1[C:10]2[C:5](=[N:6][CH:7]=[CH:8][CH:9]=2)[NH:4][CH:3]=1.[Br:11][CH2:12][CH2:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.CCOCC>C(#N)C>[BrH:11].[CH3:1][C:2]1[C:10]2[C:5]([N:6]([CH2:12][CH2:13][C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[CH:7]=[CH:8][CH:9]=2)=[N:4][CH:3]=1참가 물질
5
실험 절차
A solution of 0.3 g (2.3 mmol) 3-methylpyrrolo[2,3-b]pyridine and 0.5 g (2.7 mmol) (2-bromoethyl)benzene in 10 ml acetonitril was refluxed for 72 h. The solvent was evaporated and the solid that formed was treated with ether. Recrystalization from ethyl acetate gave 0.2 g (27%) of the title compound as a white solid.
후처리
- customThe solvent was evaporated
- customthe solid that formed
- customRecrystalization from ethyl acetate
출처 및 근거
- ORD 기록
- ord-9bb3767162c642e5a05e45274cee7029
- 출처 데이터셋
- uspto-grants-1995_08
- 특허 번호
- US05439917
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