2-Chloroacetophenone → HCID 131719075, 화합물

HRID 1756054노트

반응식

HRID 1756054 반응식
[CH3:1][O:2][C:3]1[C:11]2[C:6](=[N:7][CH:8]=[CH:9][CH:10]=2)[NH:5][C:4]=1[CH3:12].[CH2:13]([Cl:22])[C:14]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)=[O:15]>C(#N)C>[ClH:22].[CH3:1][O:2][C:3]1[C:11]2[C:6]([N:7]([CH2:13][C:14]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)=[O:15])[CH:8]=[CH:9][CH:10]=2)=[N:5][C:4]=1[CH3:12]

참가 물질

4

반응물 2

HCID 107572-ChloroacetophenoneHCID 199168183-Methoxy-2-methyl-1H-pyrrolo[2,3-b]pyridine

생성물 1

HCID 131719075HCID 131719075, 화합물수율 34.3%

시약·촉매·용매 1

HCID 6342Acetonitrile용매

실험 절차

A solution of 0,75 g (4,6 mmol) 3-methoxy-2-methylpyrrolo[2,3-b]pyridine and 0,75 g (4,8 mmol) phenacyl chloride in 50 ml acetonitrile was refluxed for 14 h. Working up in the same manner as ex. 17 gave 0,5 g (34%) of the desired product.

출처 및 근거

ORD 기록
ord-093bd02bf22346cca72c635684b1322f
출처 데이터셋
uspto-grants-1995_08
특허 번호
US05439917

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