6-Nitro-8-quinolinecarboxylic acid → 8-nitroquinoline-6-carboxylic Acid

HRID 1756501노트

반응식

HRID 1756501 반응식
[NH2:1][C:2]1[CH:12]=[CH:11][C:5]([C:6]([O:8]CC)=[O:7])=[CH:4][C:3]=1[N+:13]([O-:15])=[O:14].[C:16]([C:19]1C=C([N+]([O-])=O)C=C2[C:28]=1N=CC=C2)(O)=O>>[C:6]([C:5]1[CH:11]=[C:12]2[C:2](=[C:3]([N+:13]([O-:15])=[O:14])[CH:4]=1)[N:1]=[CH:28][CH:19]=[CH:16]2)([OH:8])=[O:7]

참가 물질

3

반응물 2

HCID 1501526-Nitro-8-quinolinecarboxylic acidHCID 3018687Benzoic acid, 4-amino-3-nitro-, ethyl ester

생성물 1

HCID 71401918-nitroquinoline-6-carboxylic Acid수율 61%

실험 절차

6-Carboxy-8-nitroquinoline was prepared from ethyl 4-amino-3-nitrobenzoate using the method described for 8-carboxy-6-nitroquinoline in example 1. (Yield: 61%).

출처 및 근거

ORD 기록
ord-80623c823d8946a396e11f0fe206c0bd
출처 데이터셋
uspto-grants-1995_08
특허 번호
US05441949

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