Pyridine → HCID 19389470, 화합물

HRID 1757047노트

반응식

HRID 1757047 반응식
[Si:1]([O:8][CH2:9][CH:10]1[O:15][C:14](=[O:16])[CH:13]=[C:12]([OH:17])[CH2:11]1)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].N1C=CC=CC=1.[C:24](Cl)(=[O:26])[CH3:25]>ClCCl>[C:24]([O:17][C:12]1[CH2:11][CH:10]([CH2:9][O:8][Si:1]([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2])[O:15][C:14](=[O:16])[CH:13]=1)(=[O:26])[CH3:25]

참가 물질

5

반응물 3

HCID 1049PyridineHCID 6367Acetyl chlorideHCID 67809616HCID 67809616, 화합물

생성물 1

HCID 19389470HCID 19389470, 화합물

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

To 6-t-butyldimethylsilyloxymethyl-5,6-dihydro-4-hydroxy-pyran-2-one (0.26 parts) in dichloromethane (3 cm3) at ambient temperature was added pyridine (0.1 parts) and then acetyl chloride (0.1 parts). After approximately 30 minutes at ambient temperature the reaction mixture was washed with water, dried over MgSO4 and evaporated to yield 4-acetoxy-6-t-butyldimethylsilyloxymethyl-5,6-dihydropyran-2-one (0.2 parts).

후처리

  1. washAfter approximately 30 minutes at ambient temperature the reaction mixture was washed with water
  2. dry with materialdried over MgSO4
  3. customevaporated

출처 및 근거

ORD 기록
ord-cc4c16edcc854448b5c8b86d690ffaff
출처 데이터셋
uspto-grants-1995_08
특허 번호
US05443970

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