Pyridine → HCID 19389482, 화합물
반응식
[OH:1][CH:2]1[CH2:7][CH:6]([CH3:8])[O:5][C:4](=[O:9])[CH2:3]1.N1C=CC=CC=1.[S:16](Cl)([CH3:19])(=[O:18])=[O:17]>ClCCl>[S:16]([O:1][CH:2]1[CH2:7][CH:6]([CH3:8])[O:5][C:4](=[O:9])[CH2:3]1)([CH3:19])(=[O:18])=[O:17]참가 물질
5
실험 절차
To a solution of 4-hydroxy-6-methyltetrahydropyran-2-one (1.5 parts) in dichloromethane (40 parts) was added pyridine (1.1 parts) and then, over 15 minutes, mesyl chloride (1.65 parts). The reaction was set aside at ambient temperature under N2 for 18 hours at which point GLC analysis indicated less than 1.5% of the starting material remained. The reaction mixture was filtered and the organic phase then washed with water before evaporating to obtain 4-mesyloxy-6-methyl-tetrahydropyran-2-one (0.5 parts).
후처리
- waitThe reaction was set aside at ambient temperature under N2 for 18 hours at which point GLC analysis
- filtrationThe reaction mixture was filtered
- washthe organic phase then washed with water
- custombefore evaporating
출처 및 근거
- ORD 기록
- ord-f4dc6e204cbf4ae0a1de9bb56f0c35c9
- 출처 데이터셋
- uspto-grants-1995_08
- 특허 번호
- US05443970
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