1-Dodecanethiol → 1-Pentafluoroethylthiododecane

HRID 1758184

반응식

HRID 1758184 반응식
[CH2:1]([SH:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].C(C1C=C(C)C=C(C(C)(C)C)N=1)(C)(C)C.FC(F)(F)S([O-])(=O)=O.[F:37][C:38]([I+]C1C=CC=CC=1)([F:43])[C:39]([F:42])([F:41])[F:40]>C(Cl)Cl>[F:37][C:38]([F:43])([S:13][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12])[C:39]([F:42])([F:41])[F:40]

참가 물질

5

반응물 3

HCID 81951-DodecanethiolHCID 988982,6-Di-tert-butyl-4-methylpyridineHCID 11488264Pentafluoroethylphenyliodonium trifluoromethanesulfonate

생성물 1

HCID 128906271-Pentafluoroethylthiododecane

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

2.0 ml of methylene chloride, 0.10 ml (0.42 mmol) of 1-dodecanethiol and 87 mg (0.42 mmol) of 2,6-di-tert-butyl-4-methylpyridine were added to a flask, and 198 mg (0.42 mmol) of pentafluoroethylphenyliodonium trifluoromethanesulfonate was added thereto in small portions while stirring at room temperature, followed by stirring at room temperature for 20 minutes. The resulting white precipitate was filtered and subjected to column chromatography of silica gel. Iodobenzene and the product were eluted with pentane and purified by gas chromatography to obtain 1-pentafluoroethylthiododecane as an oily substance. Yield, 87%.

후처리

  1. stirringby stirring at room temperature for 20 minutes
  2. filtrationThe resulting white precipitate was filtered
  3. washIodobenzene and the product were eluted with pentane
  4. custompurified by gas chromatography

출처 및 근거

ORD 기록
ord-79163db0c8f444d69b79b8419bf7bd58
출처 데이터셋
uspto-grants-1983_02
특허 번호
US04371710

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