Triglycidylglycerol → 1,2,3-Tris[2-hydroxy-3-(7,7,9,9-tetramethyl-3-octyl-2,4-dioxo-1,3,8-triazaspiro[4.5]dec-8-yl)propoxy]propane

HRID 1758205

반응식

HRID 1758205 반응식
[CH3:1][C:2]1([CH3:24])[NH:21][C:20]([CH3:23])([CH3:22])[CH2:19][C:4]2([NH:8][C:7](=[O:9])[N:6]([CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[C:5]2=[O:18])[CH2:3]1.[O:25]1[CH2:42][CH:26]1[CH2:27][O:28][CH2:29][CH:30]([CH2:36][O:37][CH2:38][CH:39]1[O:41][CH2:40]1)[O:31][CH2:32][CH:33]1[O:35][CH2:34]1>C(O)CCCCCCC>[OH:25][CH:26]([CH2:42][N:21]1[C:20]([CH3:23])([CH3:22])[CH2:19][C:4]2([NH:8][C:7](=[O:9])[N:6]([CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[C:5]2=[O:18])[CH2:3][C:2]1([CH3:1])[CH3:24])[CH2:27][O:28][CH2:29][CH:30]([O:31][CH2:32][CH:33]([OH:35])[CH2:34][N:21]1[C:20]([CH3:23])([CH3:22])[CH2:19][C:4]2([NH:8][C:7](=[O:9])[N:6]([CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[C:5]2=[O:18])[CH2:3][C:2]1([CH3:1])[CH3:24])[CH2:36][O:37][CH2:38][CH:39]([OH:41])[CH2:40][N:21]1[C:20]([CH3:23])([CH3:22])[CH2:19][C:4]2([NH:8][C:7](=[O:9])[N:6]([CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[C:5]2=[O:18])[CH2:3][C:2]1([CH3:1])[CH3:24]

참가 물질

4

반응물 2

HCID 25795TriglycidylglycerolHCID 112677117,7,9,9-Tetramethyl-3-octyl-1,3,8-triazaspiro[4.5]decane-2,4-dione

생성물 1

HCID 205105851,2,3-Tris[2-hydroxy-3-(7,7,9,9-tetramethyl-3-octyl-2,4-dioxo-1,3,8-triazaspiro[4.5]dec-8-yl)propoxy]propane

시약·촉매·용매 1

HCID 9571-Octanol용매

반응 조건

온도
180 °C

실험 절차

A mixture of 11.0 g of 7,7,9,9-tetramethyl-3-octyl-1,3,8-triazaspiro[4.5]decane-2,4-dione and 2.6 g of glycerol tris(2,3-epoxypropyl)ether in 10 ml of octanol was heated at 180° C. for 30 hours. After completion of the reaction, the reaction mixture was purified by column chromatography through silica gel eluted with ethyl acetate, giving the desired Compound No. 349 in the form of a colourless oil. The compound had an Rf value of 0.54 on thin-layer chromatography on silica gel when developed with a 10:1 by volume mixture of ethyl acetate and triethylamine.

후처리

  1. customAfter completion of the reaction
  2. customthe reaction mixture was purified by column chromatography through silica gel
  3. washeluted with ethyl acetate

출처 및 근거

ORD 기록
ord-a71dc88bbf9245bdb2dd4e207ba3866f
출처 데이터셋
uspto-grants-1983_02
특허 번호
US04371644

연결된 노트

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