HCID 20509898, 화합물 → HCID 20509920, 화합물

HRID 1758234노트

반응식

HRID 1758234 반응식
[CH3:1][O:2][CH:3]([O:17][CH3:18])[CH2:4][NH:5][CH2:6][C:7]1[CH:12]=[C:11]([CH3:13])[CH:10]=[CH:9][C:8]=1[N+:14]([O-])=O>C(O)C.[Pd]>[CH3:1][O:2][CH:3]([O:17][CH3:18])[CH2:4][NH:5][CH2:6][C:7]1[CH:12]=[C:11]([CH3:13])[CH:10]=[CH:9][C:8]=1[NH2:14]

참가 물질

4

반응물 1

HCID 20509898HCID 20509898, 화합물

생성물 1

HCID 20509920HCID 20509920, 화합물

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

The crude aminoacetal obtained in step (c) is dissolved in 700 ml of ethanol and is hydrogenated at room temperature and at atmospheric pressure, in the presence of 3 g of palladium catalyst (10% Pd on carbon). After the catalyst is filtered off and the filtrate evaporated, the heading compound remains as an orange oil, which is converted into the hydrochloride using methanolic hydrochloric acid.

후처리

  1. filtrationAfter the catalyst is filtered off
  2. customthe filtrate evaporated

출처 및 근거

ORD 기록
ord-8186f80460ea49798f8a047ceef94a27
출처 데이터셋
uspto-grants-1983_02
특허 번호
US04372956

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